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Mg-supplementation Protects Against Ritonavir-mediated Endothelial Oxidative Stress and Hepatic eNOS Downregulation

Ritonavir (RTV), a prototypical protease inhibitor currently used as a key component for anti-HIV therapy, is known for its endothelial and hepatic toxicity. The effects of RTV and Mg-supplementation on cultured bovine endothelial cells (EC) and rat hepatic endothelial nitric oxide synthase (eNOS) s...

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Bibliografiske detaljer
Main Authors: Chen, Xi, Mak, I.Tong
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960338/
https://ncbi.nlm.nih.gov/pubmed/24434120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.01.011
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