Ginsenoside Rb1 Blocks Ritonavir-Induced Oxidative Stress and eNOS Downregulation through Activation of Estrogen Receptor-Beta and Upregulation of SOD in Human Endothelial Cells

We have previously shown that ritonavir (RTV), a highly active anti-retroviral therapy (HAART) drug, can cause endothelial dysfunction through oxidative stress. Several antioxidants including ginsenoside Rb1, a compound with antioxidant effect, can effectively block this side effect of RTV in endoth...

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Udgivet i:Int J Mol Sci
Main Authors: Lü, Jian-Ming, Jiang, Jun, Jamaluddin, Md Saha, Liang, Zhengdong, Yao, Qizhi, Chen, Changyi
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358897/
https://ncbi.nlm.nih.gov/pubmed/30642080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20020294
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