EGF-Like-Domain-7 Is Required for VEGF-Induced Akt/ERK Activation and Vascular Tube Formation in an Ex Vivo Angiogenesis Assay

EGFL7 is a secreted angiogenic factor, which in contrast to the well-known secreted angiogenic molecules VEGF and FGF-2, is almost exclusively expressed by endothelial cells and may act in an autocrine fashion. Prior studies have shown EGFL7 to mediate its angiogenic effects by interfering with the...

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Detalhes bibliográficos
Main Authors: Takeuchi, Kimio, Yanai, Ryoji, Kumase, Fumiaki, Morizane, Yuki, Suzuki, Jun, Kayama, Maki, Brodowska, Katarzyna, Nakazawa, Mitsuru, Miller, Joan W., Connor, Kip M., Vavvas, Demetrios G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960138/
https://ncbi.nlm.nih.gov/pubmed/24647208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091849
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