Chaihuang-Yishen Granule Inhibits Diabetic Kidney Disease in Rats through Blocking TGF-β/Smad3 Signaling

OBJECTIVE: Increasing evidence shows that TGF-β1 is a key mediator in diabetic nephropathy (DN) and induces renal fibrosis positively by Smad3 but negatively by Smad7. However, treatment of DN by blocking the TGF-β/Smad pathway remains limited. The present study investigated the anti-fibrotic effect...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Ting Ting, Zhang, Hao Jun, Lu, Xiao Guang, Huang, Xiao Ru, Zhang, Wei Ku, Wang, Hua, Lan, Hui Yao, Li, Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960111/
https://ncbi.nlm.nih.gov/pubmed/24646636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090807
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