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Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily
Mutations in LRRK2 cause autosomal dominant Parkinson's disease (PD). LRRK2 encodes a multi-domain protein containing GTPase and kinase domains, and putative protein–protein interaction domains. Familial PD mutations alter the GTPase and kinase activity of LRRK2 in vitro. LRRK2 is suggested to...
Gorde:
Egile Nagusiak: | , , , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
Oxford University Press
2014
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959816/ https://ncbi.nlm.nih.gov/pubmed/24282027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt600 |
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