GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1.

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most common cause of autosomal dominant familial Parkinson's disease (PD) and also contribute to idiopathic PD. LRRK2 encodes a large multi-domain protein with GTPase and kinase activity. Initial data indicates that an intact fu...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Klodjan Stafa, Alzbeta Trancikova, Philip J Webber, Liliane Glauser, Andrew B West, Darren J Moore
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2012-01-01
叢編:PLoS Genetics
在線閱讀:http://europepmc.org/articles/PMC3280333?pdf=render
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍