Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily

Mutations in LRRK2 cause autosomal dominant Parkinson's disease (PD). LRRK2 encodes a multi-domain protein containing GTPase and kinase domains, and putative protein–protein interaction domains. Familial PD mutations alter the GTPase and kinase activity of LRRK2 in vitro. LRRK2 is suggested to...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stafa, Klodjan, Tsika, Elpida, Moser, Roger, Musso, Alessandra, Glauser, Liliane, Jones, Amy, Biskup, Saskia, Xiong, Yulan, Bandopadhyay, Rina, Dawson, Valina L., Dawson, Ted M., Moore, Darren J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959816/
https://ncbi.nlm.nih.gov/pubmed/24282027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt600
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