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Expanding Anfinsen’s Principle: Contributions of Synonymous Codon Selection to Rational Protein Design

[Image: see text] Anfinsen’s principle asserts that all information required to specify the structure of a protein is encoded in its amino acid sequence. However, during protein synthesis by the ribosome, the N-terminus of the nascent chain can begin to fold before the C-terminus is available. We te...

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Xehetasun bibliografikoak
Egile Nagusiak: Sander, Ian M., Chaney, Julie L., Clark, Patricia L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2014
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959793/
https://ncbi.nlm.nih.gov/pubmed/24392935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja411302m
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