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A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunity

Bacterial and viral mRNAs are often polycistronic. Akin to alternative splicing, alternative translation of polycistronic messages is a mechanism to generate protein diversity and regulate gene function. Although a few examples exist, the use of polycistronic messages in mammalian cells is not widel...

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Detalhes bibliográficos
Main Authors: Brubaker, Sky W., Gauthier, Anna E., Mills, Eric W., Ingolia, Nicholas T., Kagan, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959641/
https://ncbi.nlm.nih.gov/pubmed/24529381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.01.021
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