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A loss-of-function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients
Dysregulation of the antiviral immune response may contribute to autoimmune diseases. Here, we hypothesized that altered expression or function of MAVS, a key molecule downstream of the viral sensors RIG-I and MDA-5, may impair antiviral cell signalling and thereby influence the risk for systemic lu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395111/ https://ncbi.nlm.nih.gov/pubmed/21268286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201000120 |
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