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Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-α induction pathway

Systemic administration of adenovirus and adenovirus vectors induces a robust innate and adaptive immune response in a variety of animal models. In tumor necrosis factor (TNF)(-/-) mice, a diminished immune response to adenovirus (Ad) infection has been attributed to compromised dendritic cell (DC)...

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Main Authors: Philpott, Nicola J., Nociari, Marcelo, Elkon, Keith B., Falck-Pedersen, Erik
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC395946/
https://ncbi.nlm.nih.gov/pubmed/15071185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308368101
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