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Influence of Fiber Detargeting on Adenovirus-Mediated Innate and Adaptive Immune Activation

The major adenovirus (Ad) capsid proteins hexon, penton, and fiber influence the efficiency and tropism of gene transduction by Ad vectors. Fiber is the high-affinity receptor binding protein that serves to mediate cell attachment in vitro when using coxsackie-adenovirus receptor (CAR)-containing ce...

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Hlavní autoři: Schoggins, John W., Nociari, Marcelo, Philpott, Nicola, Falck-Pedersen, Erik
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212603/
https://ncbi.nlm.nih.gov/pubmed/16140740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11627-11637.2005
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