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Sensing Infection by Adenovirus: Toll-Like Receptor-Independent Viral DNA Recognition Signals Activation of the Interferon Regulatory Factor 3 Master Regulator

Infection with adenovirus vectors (AdV) results in rapid activation of innate immunity, which serves the dual purpose of stimulating inflammatory antiviral host defenses and the adaptive immune system. Viral recognition by macrophages, dendritic cells, and other cell types requires an ability to sen...

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Main Authors: Nociari, Marcelo, Ocheretina, Oksana, Schoggins, John W., Falck-Pedersen, Erik
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866159/
https://ncbi.nlm.nih.gov/pubmed/17251283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02685-06
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