A DNA polymerase β mutant from colon cancer cells induces mutations
Previous investigations have shown that ≈35% of the 90 tumors analyzed to date contain mutations within the DNA polymeraseβ (pol β) gene. The existence of pol β mutations in a substantial fraction of human tumors studied suggests a link between DNA pol β and cancer. A DNA pol β variant, in which Lys...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395925/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15075389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308571101 |
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