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Evolutionarily conserved intracellular gate of voltage-dependent sodium channels

Members of the voltage-gated ion channel superfamily (VGIC) regulate ion flux and generate electrical signals in excitable cells by opening and closing pore gates. The location of the gate in voltage-gated sodium channels, a founding member of this superfamily, remains unresolved. Here we explore th...

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Autors principals: Oelstrom, Kevin, Goldschen-Ohm, Marcel P., Holmgren, Miguel, Chanda, Baron
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959192/
https://ncbi.nlm.nih.gov/pubmed/24619022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4420
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