The C-terminal region of human angiogenin has a dual role in enzymatic activity.

The ribonucleolytic activity of angiogenin (Ang) is essential to Ang's capacity to induce blood vessel formation. Previous x-ray diffraction and mutagenesis results have shown that the active site of the human protein is obstructed by Gln-117 and imply that the C-terminal region of Ang must undergo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Russo, N, Nobile, V, Di Donato, A, Riordan, J F, Vallee, B L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622921/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3243
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