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The C-terminal region of human angiogenin has a dual role in enzymatic activity.

The ribonucleolytic activity of angiogenin (Ang) is essential to Ang's capacity to induce blood vessel formation. Previous x-ray diffraction and mutagenesis results have shown that the active site of the human protein is obstructed by Gln-117 and imply that the C-terminal region of Ang must undergo...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Russo, N, Nobile, V, Di Donato, A, Riordan, J F, Vallee, B L
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1996
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39590/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622921/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3243
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