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NRF2-regulation in brain health and disease: implication of cerebral inflammation

The nuclear factor erythroid 2 related factor 2 (NRF2) is a key regulator of endogenous inducible defense systems in the body. Under physiological conditions NRF2 is mainly located in the cytoplasm. However, in response to oxidative stress, NRF2 translocates to the nucleus and binds to specific DNA...

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Main Authors: Sandberg, Mats, Patil, Jaspal, D’Angelo, Barbara, Weber, Stephen G, Mallard, Carina
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958930/
https://ncbi.nlm.nih.gov/pubmed/24262633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.11.004
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