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NRF2-regulation in brain health and disease: implication of cerebral inflammation

The nuclear factor erythroid 2 related factor 2 (NRF2) is a key regulator of endogenous inducible defense systems in the body. Under physiological conditions NRF2 is mainly located in the cytoplasm. However, in response to oxidative stress, NRF2 translocates to the nucleus and binds to specific DNA...

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Bibliographic Details
Main Authors: Sandberg, Mats, Patil, Jaspal, D’Angelo, Barbara, Weber, Stephen G, Mallard, Carina
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958930/
https://ncbi.nlm.nih.gov/pubmed/24262633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.11.004
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