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NRF2-regulation in brain health and disease: implication of cerebral inflammation
The nuclear factor erythroid 2 related factor 2 (NRF2) is a key regulator of endogenous inducible defense systems in the body. Under physiological conditions NRF2 is mainly located in the cytoplasm. However, in response to oxidative stress, NRF2 translocates to the nucleus and binds to specific DNA...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3958930/ https://ncbi.nlm.nih.gov/pubmed/24262633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.11.004 |
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