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The DNA intercalators ethidium bromide and propidium iodide also bind to core histones
Eukaryotic DNA is compacted in the form of chromatin, in a complex with histones and other non-histone proteins. The intimate association of DNA and histones in chromatin raises the possibility that DNA-interactive small molecules may bind to chromatin-associated proteins such as histones. Employing...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3958746/ https://ncbi.nlm.nih.gov/pubmed/24649406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.02.006 |
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