Lysosomal Destabilization Contributes to Apoptosis of Germinal Center B-lymphocytes

During germinal center (GC) reactions, B-lymphocytes with high-affinity B-cell receptors are selected. Regulation of apoptosis is a key process in selecting such wanted B-cells and in eliminating B-cells with unwanted specificities. In this paper, we show that apoptosis in human GC B-cells involves...

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Main Authors: van Nierop, Kirsten, Muller, Femke J.M., Stap, Jan, Van Noorden, Cornelis J.F., van Eijk, Marco, de Groot, Cornelis
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958119/
https://ncbi.nlm.nih.gov/pubmed/16957167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.6A6967.2006
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