Загрузка...

An Increase in Acid Resistance of Foot-and-Mouth Disease Virus Capsid Is Mediated by a Tyrosine Replacement of the VP2 Histidine Previously Associated with VP0 Cleavage

The foot-and-mouth disease virus (FMDV) capsid is highly acid labile, but introduction of amino acid replacements, including an N17D change in VP1, can increase its acid resistance. Using mutant VP1 N17D as a starting point, we isolated a virus with higher acid resistance carrying an additional repl...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Vázquez-Calvo, Angela, Caridi, Flavia, Sobrino, Francisco, Martín-Acebes, Miguel A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958075/
https://ncbi.nlm.nih.gov/pubmed/24352460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03222-13
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!