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The pH Stability of Foot-and-Mouth Disease Virus Particles Is Modulated by Residues Located at the Pentameric Interface and in the N Terminus of VP1

The picornavirus foot-and-mouth disease virus (FMDV) is the etiological agent of a highly contagious disease that affects important livestock species. The FMDV capsid is highly acid labile, and viral particles lose infectivity due to their disassembly at pH values slightly below neutrality. This aci...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Caridi, Flavia, Vázquez-Calvo, Angela, Sobrino, Francisco, Martín-Acebes, Miguel A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442502/
https://ncbi.nlm.nih.gov/pubmed/25762735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03358-14
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