Nonfunctional Variant 3 Factor H Binding Proteins as Meningococcal Vaccine Candidates

Neisseria meningitidis is a human-specific pathogen and leading cause of meningitis and septicemia. Factor H binding protein (fHbp), a virulence factor which protects N. meningitidis from innate immunity by binding the human complement regulator factor H (fH) with high affinity, is also a key antige...

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Detalhes bibliográficos
Main Authors: van der Veen, Stijn, Johnson, Steven, Jongerius, Ilse, Malik, Talat, Genovese, Alessia, Santini, Laura, Staunton, David, Ufret-Vincenty, Rafael L., Pickering, Matthew C., Lea, Susan M., Tang, Christoph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958001/
https://ncbi.nlm.nih.gov/pubmed/24379280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01183-13
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