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Development and Preclinical Evaluation of a Trivalent, Formalin-Inactivated Shigella Whole-Cell Vaccine

Studies were undertaken to manufacture a multivalent Shigella inactivated whole-cell vaccine that is safe, effective, and inexpensive. By using several formalin concentrations, temperatures, and incubation periods, an optimized set of inactivation conditions was established for Shigella flexneri 2a,...

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Bibliografski detalji
Glavni autori: Kaminski, R. W., Wu, M., Turbyfill, K. R., Clarkson, K., Tai, B., Bourgeois, A. L., Van De Verg, L. L., Walker, R. I., Oaks, E. V.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957668/
https://ncbi.nlm.nih.gov/pubmed/24403527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00683-13
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