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Assembly, Biochemical Characterization, Immunogenicity, Adjuvanticity, and Efficacy of Shigella Artificial Invaplex

The native Invaplex (Invaplex(NAT)) vaccine and adjuvant is an ion exchange-purified product derived from the water extract of virulent Shigella species. The key component of Invaplex(NAT) is a high-molecular-mass complex (HMMC) consisting of the Shigella lipopolysaccharide (LPS) and the invasin pro...

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Publicat a:mSphere
Autors principals: Turbyfill, K. Ross, Clarkson, Kristen A., Vortherms, Anthony R., Oaks, Edwin V., Kaminski, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874444/
https://ncbi.nlm.nih.gov/pubmed/29600284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00583-17
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