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A Mechanistic Investigation of the C-Terminal Redox Motif of Thioredoxin Reductase from Plasmodium falciparum

[Image: see text] High-molecular mass thioredoxin reductases (TRs) are pyridine nucleotide disulfide oxidoreductases that catalyze the reduction of the disulfide bond of thioredoxin (Trx). Trx is responsible for reducing multiple protein disulfide targets in the cell. TRs utilize reduced β-nicotinam...

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Detalhes bibliográficos
Main Authors: Snider, Gregg W., Dustin, Christopher M., Ruggles, Erik L., Hondal, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957191/
https://ncbi.nlm.nih.gov/pubmed/24400600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400931k
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