A Sustained Depressive State Promotes a Guanfacine Reversible Susceptibility to Alcohol Seeking in Rats

High rates of comorbidity between alcohol use disorder (AUD) and major depressive disorder (MDD) are reported. Preclinical models examining effects of primary depression on secondary AUD are currently absent, preventing adequate testing of drug treatment. Here, we combined social defeat-induced pers...

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Detalhes bibliográficos
Main Authors: Riga, Danai, Schmitz, Leanne JM, van der Harst, Johanneke E, van Mourik, Yvar, Hoogendijk, Witte JG, Smit, August B, De Vries, Taco J, Spijker, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957105/
https://ncbi.nlm.nih.gov/pubmed/24192553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.311
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