A Sustained Depressive State Promotes a Guanfacine Reversible Susceptibility to Alcohol Seeking in Rats

High rates of comorbidity between alcohol use disorder (AUD) and major depressive disorder (MDD) are reported. Preclinical models examining effects of primary depression on secondary AUD are currently absent, preventing adequate testing of drug treatment. Here, we combined social defeat-induced pers...

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Bibliografske podrobnosti
Main Authors: Riga, Danai, Schmitz, Leanne JM, van der Harst, Johanneke E, van Mourik, Yvar, Hoogendijk, Witte JG, Smit, August B, De Vries, Taco J, Spijker, Sabine
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957105/
https://ncbi.nlm.nih.gov/pubmed/24192553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.311
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