A Sustained Depressive State Promotes a Guanfacine Reversible Susceptibility to Alcohol Seeking in Rats

High rates of comorbidity between alcohol use disorder (AUD) and major depressive disorder (MDD) are reported. Preclinical models examining effects of primary depression on secondary AUD are currently absent, preventing adequate testing of drug treatment. Here, we combined social defeat-induced pers...

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Bibliografiska uppgifter
Huvudupphovsmän: Riga, Danai, Schmitz, Leanne JM, van der Harst, Johanneke E, van Mourik, Yvar, Hoogendijk, Witte JG, Smit, August B, De Vries, Taco J, Spijker, Sabine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2014
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957105/
https://ncbi.nlm.nih.gov/pubmed/24192553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.311
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