WaveCNV: allele-specific copy number alterations in primary tumors and xenograft models from next-generation sequencing

Motivation: Copy number variations (CNVs) are a major source of genomic variability and are especially significant in cancer. Until recently microarray technologies have been used to characterize CNVs in genomes. However, advances in next-generation sequencing technology offer significant opportunit...

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Bibliographic Details
Main Authors: Holt, Carson, Losic, Bojan, Pai, Deepa, Zhao, Zhen, Trinh, Quang, Syam, Sujata, Arshadi, Niloofar, Jang, Gun Ho, Ali, Johar, Beck, Tim, McPherson, John, Muthuswamy, Lakshmi B.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957071/
https://ncbi.nlm.nih.gov/pubmed/24192544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt611
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