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Deconstructing stem cell population heterogeneity: Single-cell analysis and modeling approaches

Isogenic stem cell populations display cell-to-cell variations in a multitude of attributes including gene or protein expression, epigenetic state, morphology, proliferation and proclivity for differentiation. The origins of the observed heterogeneity and its roles in the maintenance of pluripotency...

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Bibliografiske detaljer
Main Authors: Wu, Jincheng, Tzanakakis, Emmanuel S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956452/
https://ncbi.nlm.nih.gov/pubmed/24035899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2013.09.001
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