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Distinct Allelic Patterns of Nanog Expression Impart Embryonic Stem Cell Population Heterogeneity

Nanog is a principal pluripotency regulator exhibiting a disperse distribution within stem cell populations in vivo and in vitro. Increasing evidence points to a functional role of Nanog heterogeneity on stem cell fate decisions. Allelic control of Nanog gene expression was reported recently in mous...

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Detalhes bibliográficos
Main Authors: Wu, Jincheng, Tzanakakis, Emmanuel S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708867/
https://ncbi.nlm.nih.gov/pubmed/23874182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003140
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