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Deconstructing stem cell population heterogeneity: Single-cell analysis and modeling approaches
Isogenic stem cell populations display cell-to-cell variations in a multitude of attributes including gene or protein expression, epigenetic state, morphology, proliferation and proclivity for differentiation. The origins of the observed heterogeneity and its roles in the maintenance of pluripotency...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956452/ https://ncbi.nlm.nih.gov/pubmed/24035899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2013.09.001 |
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