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A novel cell-based high-throughput screen for inhibitors of HIV-1 gene expression and budding identifies the cardiac glycosides

OBJECTIVES: Highly active antiretroviral therapy (HAART) is the mainstay of treatment for HIV-1 infection. While current HAART regimens have been extremely effective, issues of associated toxicity, cost and resistance remain and there is a need for novel antiretroviral compounds to complement the ex...

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Detalhes bibliográficos
Main Authors: Laird, Gregory M., Eisele, Evelyn E., Rabi, S. Alireza, Nikolaeva, Daria, Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956374/
https://ncbi.nlm.nih.gov/pubmed/24275119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt471
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