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Phase II trial of patupilone in patients with brain metastases from breast cancer

BACKGROUND: For patients with progressive breast cancer brain metastasis (BCBM) after whole brain radiotherapy (WBRT), few options exist. Patupilone is an epothilone that crosses the blood–brain barrier. We hypothesized that patupilone would produce a 35% 3-month CNS progression-free survival in wom...

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Detalhes bibliográficos
Main Authors: Peereboom, David M., Murphy, Conleth, Ahluwalia, Manmeet S., Conlin, Alison, Eichler, April, Van Poznak, Catherine, Baar, Joseph, Elson, Paul, Seidman, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956359/
https://ncbi.nlm.nih.gov/pubmed/24470546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not305
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