GLTSCR2/PICT1 links mitochondrial stress and Myc signaling

Mitochondrial defects underlie a multitude of human diseases. Genetic manipulation of mitochondrial regulatory pathways represents a potential therapeutic approach. We have carried out a high-throughput overexpression screen for genes that affect mitochondrial abundance or activity using flow-cytome...

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Bibliografiska uppgifter
Huvudupphovsmän: Yoon, John C., Ling, Alvin J. Y., Isik, Meltem, Lee, Dong-Young Donna, Steinbaugh, Michael J., Sack, Laura M., Boduch, Abigail N., Blackwell, T. Keith, Sinclair, David A., Elledge, Stephen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956149/
https://ncbi.nlm.nih.gov/pubmed/24556985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400705111
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