p53 oligomerization and DNA looping are linked with transcriptional activation.

We examined the role of p53 oligomerization in DNA binding and in transactivation. By conventional electron microscopy (EM) and scanning transmission EM, we find that wild-type tetramers contact 18-20 bp at single or tandem 19 bp consensus sequences and also stack in apparent register, tetramer on t...

詳細記述

保存先:
書誌詳細
主要な著者: Stenger, J E, Tegtmeyer, P, Mayr, G A, Reed, M, Wang, Y, Wang, P, Hough, P V, Mastrangelo, I A
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC395578/
https://ncbi.nlm.nih.gov/pubmed/7813439
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