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Ordering gene function: the interpretation of epistasis in regulatory hierarchies

The order of action of genes in a regulatory hierarchy that is governed by a signal can often be determined by the method of epistasis analysis, in which the phenotype of a double mutant is compared with that of single mutants. The epistatic mutation may be in either the upstream or the downstream g...

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Bibliographic Details
Main Authors: AVERY, LEON, WASSERMAN, STEVEN
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955268/
https://ncbi.nlm.nih.gov/pubmed/1365397
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