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HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell–mediated killing

HIV up-regulates cell-surface expression of specific ligands for the activating NKG2D receptor, including ULBP-1, -2, and -3, but not MICA or MICB, in infected cells both in vitro and in vivo. However, the viral factor(s) involved in NKG2D ligand expression still remains undefined. HIV-1 Vpr activat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Richard, Jonathan, Sindhu, Sardar, Pham, Tram N. Q., Belzile, Jean-Philippe, Cohen, Éric A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955183/
https://ncbi.nlm.nih.gov/pubmed/20008788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-237370
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