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HIV-1 Vpu Downmodulates ICAM-1 Expression, Resulting in Decreased Killing of Infected CD4(+) T Cells by NK Cells

HIV-1 Vpu is known to alter the expression of numerous cell surface molecules. Given the ever-increasing list of Vpu targets identified to date, we undertook a proteomic screen to discover novel cell membrane proteins modulated by this viral protein. Plasma membrane proteome isolates from Vpu-induci...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sugden, Scott M., Pham, Tram N. Q., Cohen, Éric A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5375687/
https://ncbi.nlm.nih.gov/pubmed/28148794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02442-16
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