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c-Myc induces cellular susceptibility to the cytotoxic action of TNF-alpha.

Tumor necrosis factor-alpha (TNF) is a multifunctional cytokine which is cytotoxic for some tumor cells and transformed cells. The molecular mechanisms which render transformed and tumor cells sensitive to the cytotoxic action of TNF are unclear. We show here that an increased expression of the c-My...

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Detalhes bibliográficos
Main Authors: Klefstrom, J, Västrik, I, Saksela, E, Valle, J, Eilers, M, Alitalo, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395501/
https://ncbi.nlm.nih.gov/pubmed/7957110
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