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Glibenclamide in Cerebral Ischemia and Stroke

The sulfonylurea receptor 1 (Sur1)–transient receptor potential 4 (Trpm4) channel is an important molecular element in focal cerebral ischemia. The channel is upregulated in all cells of the neurovascular unit following ischemia, and is linked to microvascular dysfunction that manifests as edema for...

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Autors principals: Simard, J. Marc, Sheth, Kevin N., Kimberly, W. Taylor, Stern, Barney J., del Zoppo, Gregory J., Jacobson, Sven, Gerzanich, Volodymyr
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954940/
https://ncbi.nlm.nih.gov/pubmed/24132564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12028-013-9923-1
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