Does inhibiting Sur1 complement rt-PA in cerebral ischemia?

Hemorrhagic transformation (HT) associated with recombinant tissue plasminogen activator (rt-PA) complicates and limits its use in stroke. Here, we provide a focused review on the involvement of matrix metalloproteinase 9 (MMP-9) in rt-PA–associated HT in cerebral ischemia, and we review emerging ev...

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Detalhes bibliográficos
Main Authors: Simard, J. Marc, Geng, Zhihua, Silver, Frank L., Sheth, Kevin N., Kimberly, W. Taylor, Stern, Barney J., Colucci, Mario, Gerzanich, Volodymyr
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507518/
https://ncbi.nlm.nih.gov/pubmed/22994227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06705.x
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