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The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans

Parkinson's disease (PD) is a neurodegenerative brain disorder characterized by selective dopaminergic (DAergic) cell loss that results in overt motor and cognitive deficits. Current treatment options exist to combat PD symptomatology, but are unable to directly target its pathogenesis due to a...

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Detalhes bibliográficos
Main Authors: Bornhorst, Julia, Chakraborty, Sudipta, Meyer, Sören, Lohren, Hanna, Brinkhaus, Sigrid Groβe, Knight, Adam L., Caldwell, Kim A., Caldwell, Guy A., Karst, Uwe, Schwerdtle, Tanja, Bowman, Aaron, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954834/
https://ncbi.nlm.nih.gov/pubmed/24452053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mt00325f
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