Role of Caenorhabditis elegans AKT1/2 and SGK-1 in Manganese Toxicity

Excessive levels of the essential metal manganese (Mn) may cause a syndrome similar to Parkinson’s disease. The model organism Caenorhabditis elegans mimicks some of Mn effects in mammals, including dopaminergic neurodegeneration, oxidative stress and increased levels of Akt. The evolutionarily cons...

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Bibliografske podrobnosti
izdano v:Neurotox Res
Main Authors: Peres, Tanara V., Arantes, Leticia, Miah, Mahfuzur R., Bornhorst, Julia, Schwerdtle, Tanja, Bowman, Aaron B., Leal, Rodrigo B., Aschner, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286235/
https://ncbi.nlm.nih.gov/pubmed/29882004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-018-9915-1
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