Combined exposure to methylmercury and manganese during L1 larval stage causes motor dysfunction, cholinergic and monoaminergic up-regulation and oxidative stress in L4 Caenorhabditis elegans

Humans are exposed simultaneously to a variety of neurotoxic agents, including manganese (Mn) and methylmercury (MeHg). Therefore, the study of combined exposures to toxicants is timely. This work aimed to study changes in cholinergic system focusing on acetylcholinesterase (ace-2), monoaminergic sy...

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Detalhes bibliográficos
Publicado no:Toxicology
Main Authors: Chitolina Schetinger, Maria Rosa, Peres, Tanara V., Arantes, Letícia P., Carvalho, Fabiano, Dressler, Valderi, Heidrich, Graciela, Bowman, Aaron B., Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226008/
https://ncbi.nlm.nih.gov/pubmed/30336192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2018.10.006
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