Mutation detection with MutH, MutL, and MutS mismatch repair proteins.
Escherichia coli methyl-directed mismatch repair is initiated by MutS-, MutL-, and ATP-dependent activation of MutH endonuclease, which cleaves at d(GATC) sites in the vicinity of a mismatch. This reaction provides an efficient method for detection of mismatches in heteroduplexes produced by hybridi...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633074/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.4374 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|