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Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes

Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form of non-Hodgkin lymphoma with variable biology and clinical behavior. The current classification does not fully explain the biological and clinical heterogeneity of DLBCLs. In this study, we carried out genomewide DNA methylatio...

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Autors principals: Chambwe, Nyasha, Kormaksson, Matthias, Geng, Huimin, De, Subhajyoti, Michor, Franziska, Johnson, Nathalie A., Morin, Ryan D., Scott, David W., Godley, Lucy A., Gascoyne, Randy D., Melnick, Ari, Campagne, Fabien, Shaknovich, Rita
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954051/
https://ncbi.nlm.nih.gov/pubmed/24385541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-509885
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