Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle()

Insulin resistance is associated with mitochondrial dysfunction, but the mechanism by which mitochondria inhibit insulin-stimulated glucose uptake into the cytoplasm is unclear. The mitochondrial permeability transition pore (mPTP) is a protein complex that facilitates the exchange of molecules betw...

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Detalhes bibliográficos
Main Authors: Taddeo, E.P., Laker, R.C., Breen, D.S., Akhtar, Y.N., Kenwood, B.M., Liao, J.A., Zhang, M., Fazakerley, D.J., Tomsig, J.L., Harris, T.E., Keller, S.R., Chow, J.D., Lynch, K.R., Chokki, M., Molkentin, J.D., Turner, N., James, D.E., Yan, Z., Hoehn, K.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953683/
https://ncbi.nlm.nih.gov/pubmed/24634818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.11.003
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